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Profile Last Updated: 06/01/2021 Grant Information Last Updated: 07/23/2021

James S. McDonnell Foundation

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Purpose and Activities

JSMF believes that private philanthropic support for science is most effective when it invests in the acquisition of new knowledge and in the responsible application of knowledge for solving the real world problems. The 21st Century Science Initiative, the foundation's revised program and funding strategy, will award two types of grants in three program areas. The three program areas are Mathematical & Complex Systems Approaches for Brain Cancer Research, Studying Complex Systems, and Understanding Human Cognition. Projects supported through the 21st Century Science Initiative are expected to meet highly selective intellectual standards.


Established in MO - In 1950, James S. McDonnell, Jr. established the McDonnell Foundation, incorporated as a private foundation. The foundation has pursued his goals by supporting scientific, educational, and charitable causes locally, nationally, and internationally. The organization was renamed the James S. McDonnell Foundation in 1984 in honor of its founder and was reorganized in 2002 with amended by-laws by its current board members, descendants of James S. McDonnell.


James S. McDonnell Foundation

Independent foundation




1034 S. Brentwood Blvd., Ste. 1850 St. Louis, MO United States 63117-1229

Contact Information